About Angela Ardolino
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Cushing’s Disease is an endocrine disorder, and is also known as hypercortisolism or hyperadrenocorticism. It causes your dog’s body to make too much of a hormone called cortisol. Cortisol is a hormone that helps control stress, weight, infections, and blood sugar. Too much cortisol, or too little, can wreak havoc on your pet’s overall wellbeing.
Research on CBD for Cushing’s Disease in Dogs
The traditional treatment for Cushing’s Disease in dogs is surgery to remove the tumor. Veterinarians may also prescribe hormone-regulating medications. However, surgery can be invasive and dangerous, especially in older dogs, and prescribed medications can cause additional side-effects.
Yet another research study conducted by the Department of Physiology, School of Medicine, at Southern Illinois University. There researchers found that CBD could have profound effects on the release of hormones, including cortisol.
In a research study conducted by the A.B. Hancock Jr. Memorial Laboratory for Cancer Research, Vanderbilt Institute of Chemical Biology, Vanderbilt Ingram Comprehensive Cancer Center, and Vanderbilt University School of Medicine. In the study, researchers concluded that the effects of CBD are promising in the treatment of cancer and tumors.
When something is going on with your pet, it can be overwhelming to figure out the issue and get a diagnosis. It can be even more confusing to know how to treat it and keep your pet feeling their best. We’re here to help.
And finally, some research suggests that CBD oil may be able to help reduce hormonal imbalances and lower cortisol levels in the body. Cannabinoid receptors, which are affected by CBD, are expressed throughout the body, including the pituitary gland, and are able to influence the stress response.
Hair loss, primarily on the body rather than legs
Adrenal-dependent Cushing’s disease results from disruption to the adrenal glands themselves—again, usually due to a tumor. This causes the glands to become confused and overproduce cortisol, which builds in the bloodstream.
And does it work?
Treatment for Cushing’s will depend partly on the source behind your dog’s increased cortisol levels.
Completely curing Cushing’s disease requires removing the tumor or other disruption to the affected gland before the tumor spreads. In adrenal-dependent cases, this may be possible through surgery, however, surgical techniques for the pituitary-dependent disease are not viable options for dogs in the majority of situations.
Cushing’s disease occurs when cortisol levels increase, due to the presence of a tumor or other disruption to the adrenal or pituitary glands.
Second, CBD oil may be able to counteract the effects of increased cortisol levels. Working through the endocannabinoid system, CBD is able to affect receptors in the brain, nervous system, and gastrointestinal tract, reducing inflammation and irritation.
Most of the time it is diagnosed when a dog already has full-blown Cushing’s disease, at which stage it is irreversible and incurable.
As I mentioned earlier, there’s limited research into the possibility of using CBD to treat this issue.
I would recommend HolistaPet’s CBD Pet Tincture for treating this specific type of ailment, and to use as an overall general wellness supplement.
How is Cushing’s Normally Treated?
Some possible causes of this disease include:
In excess levels, however, cortisol can cause severe muscle, skin, and bone breakdown.
Gryphon, for example, is a 10-year-old Tibetan Mastiff who suffers from Cushing’s and severe arthritis.
In response to the stressful stimuli, the hypothalamus produces a hormone known as CRH (corticotropin-releasing hormone), which signals the pituitary gland to produce another hormone known as ACTH (adrenocorticotropic-releasing hormone).