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By now you’re probably familiar with cannabinoids, especially the most common ones, THC and CBD. But you likely haven’t heard of cannabichromene, also known as CBC. Discovered over 50 years ago, CBC is considered one of the “big six” cannabinoids prominent in medical research. It doesn’t get as much attention, but CBC’s benefits are extremely promising.

In another amazing display of the entourage effect, CBC appears to work in conjunction with both THC and CBD to deliver a trifecta of antidepressant properties.

CBC Works With Other Cannabinoids

Cannabichromene has been shown to block pain and inflammation associated with collagen-induced osteoarthritis. Cannabinoids like CBC act on inflammation differently than non-steroidal anti-inflammatory drugs (NSAIDs) do, and don’t have the side effects of these medications. In another example of the entourage effect, CBC in combination with THC had significant anti-inflammatory response in a recent animal study; together, the two cannabinoids produced a much greater effect on inflammation than by themselves.

The specific plant enzymes cascade and “direct” the breakdown product into one of the three lines. For CBC, it converts from CBGA into cannabichrome carboxylic acid (CBCA), and then finally to CBC after exposure to heat or ultraviolet light.

CBC has the same origins as both THC and CBD do in that they all stem from cannabigerolic acid (CBGA). Cannabis plants produce CBGA, the precursor to three major cannabinoids: tetrahydrocannabinolic acid (THCA), cannabidiolic acid (CBDA), and cannabichromenic acid (CBCA).

The CBD market is still the wild wild west. Anyone can make it, sell it and slap a misleading or even outright false label on their product. With so many brands to choose from, it can be hard to determine who to trust. Instead of just claiming our products are the best, we show you. All of our products are backed by our batch tracking system so you can view a certificate of analysis for the product in your hand. Yes, many companies provide a COA, and some are legit. However, many are showing you an old, irrelevant COA. Even some of the biggest names in the business have gotten busted for inaccurate lab reports! We put a tracking number on all products that you can use to view the COA specific to each batch produced. What about 3rd party testing? Here’s what we can say about that… we are a lab, and we provide analytical services just like other labs, therefore, it is both cost-effective and of a higher quality to use our own facility. This is not a compromise. It is the only way we can provide the best quality and best value possible. Therefore, it is directly in line with our core values and mission as a company. Occasionally, a CBD vetting company will have our products tested by multiple 3rd-party labs, and guess what they find? We have been awarded the highest standards for perfect scores. One company (CBD Examine) went so far as to detail that per cannabinoid volume, our tinctures are the best quality and value on the market.

Ingredients: Organic Coconut Oil, Full Spectrum Hemp Oil, Vegetable Glycerin, Gelatin (Bovine)

Our Relief Formula CBC softgels are a full spectrum, whole-plant extract that features a 3:1 ratio of CBD to CBC. Discovered over 50 years ago, CBC is considered one of the “big six” cannabinoids prominent in medical research. It’s thought to have the same potential as CBD as well as its own unique uses.*

Lab Results

Start with one capsule per day and increase to up to two capsules daily. We recommend spacing out doses in the morning and evening. Keep in mind that CBD capsules are slower-acting than other methods.* Be prepared for a more subtle, gradual onset.*

Extract Labs is privately owned. When you shop with us, you are purchasing a product made by the hardest working people in the industry. We are all obsessed with making the best CBD products available to everyone. Your hard-earned money doesn’t go into the pockets of investors. It goes towards upgrading equipment to lower product costs, research into new cannabinoids, and helps keep a roof over the heads of our 40-something employees.

View and download your product’s Certificate of Analysis (COA). Locate the batch ID on the product label and click the corresponding link to see the results for your specific item. COAs detail potency, cannabinoid profile, and purity from contaminants.

Please consult a physician before use.

Udoh M, Santiago M, Devenish S, McGregor IS, Connor M. Cannabichromene is a cannabinoid CB2 receptor agonist. Br J Pharmacol. 2019;176(23):4537-4547. View abstract.

De Petrocellis L, Ligresti A, Moriello AS, et al. Effects of cannabinoids and cannabinoid-enriched Cannabis extracts on TRP channels and endocannabinoid metabolic enzymes. Br J Pharmacol. 2011;163(7):1479-94. View abstract.

We currently have no information for CANNABICHROMENE (CBC) overview .

Interactions ?

De Petrocellis L, Orlando P, Moriello AS, et al. Cannabinoid actions at TRPV channels: effects on TRPV3 and TRPV4 and their potential relevance to gastrointestinal inflammation. Acta Physiol (Oxf). 2012;204(2):255-66. View abstract.

Shinjyo N, Di Marzo V. The effect of cannabichromene on adult neural stem/progenitor cells. Neurochem Int. 2013;63(5):432-7. View abstract.

Wirth PW, Watson ES, ElSohly M, Turner CE, Murphy JC. Anti-inflammatory properties of cannabichromene. Life Sci. 1980;26(23):1991-5. View abstract.

Izzo AA, Capasso R, Aviello G, et al. Inhibitory effect of cannabichromene, a major non-psychotropic cannabinoid extracted from Cannabis sativa, on inflammation-induced hypermotility in mice. Br J Pharmacol. 2012;166(4):1444-60. View abstract.