“One of the challenges is we don’t know what dose can alleviate what anti-inflammatory or immune-related conditions,” he continued.
Cannabinoids, including CBD, are believed to be anti-inflammatory. Several studies in cells, rodents, and humans support the idea that CBD may be an effective anti-inflammatory, but more research is needed to determine how it works and the best applications for specific types of inflammation.
There is some evidence supporting the idea that CBD can act as an anti-inflammatory treatment for some diseases.
Human health: What do studies say?
CBD also appears to affect a class of molecules important to the inflammation process called cytokines. CBD tends to reduce the effects of pro-inflammatory cytokines, thereby reducing inflammation.
A 2008 study in mice found that CBD prevented the onset of type 1 diabetes, an inflammatory autoimmune disease that attacks the beta cells of the pancreas.
Inflammation plays an important role in a number of diseases, including asthma, allergies, inflammatory bowel disease, celiac disease, and a number of autoimmune conditions, as well as in other seemingly unrelated conditions, such as cancer, heart disease, and diabetes. Could CBD’s anti-inflammatory effects be used in any of these applications?
Such medications have risks and side effects, however. Some people choose to take a more preventative approach to treating inflammation, such as consuming an anti-inflammatory diet, and taking anti-inflammatory supplements. Could CBD contribute to a more natural approach to treating inflammation?
Stacia Woodcock, a pharmacist at Curaleaf New York, which sells CBD products, points out that it may take some time for CBD oil to exert its anti-inflammatory effects on the body.
Riggle emphasizes that the mechanisms by which CBD acts on the body, its specific applications, and appropriate doses require further study. That being said, he acknowledges that CBD represents a low-risk, high-reward treatment for inflammation, as it is non-toxic and has minor side effects.
Acute inflammation occurs following an injury, infection, or illness. The immune system unleashes immune cells to the affected area to protect it, causing redness and swelling.
What the experts say
However, not everyone who has turned to CBD to help with their inflammation has experienced benefits.
While these results are promising and most FDA-approved medication is initially tested on animals, rigorous clinical trials on humans are needed to move CBD from alternative treatment to approved medication.
“Overall, the research literature indicates that cannabinoids, including CBD, could potentially be very effective anti-inflammatory agents for nervous tissue inflammation, inflammatory bowel disease, arthritis, vascular inflammation and certain types of cancers that are triggered by chronic inflammation,” Riggle told Weedmaps.
CBD shows potential as a plant-derived anti-inflammatory without the side effects of medications. Photo by: Gina Coleman/Weedmaps
Consuming CBD through oral administration does have lower peak plasma levels . Still, the effects last for a more extended time than smoking CBD-rich hemp and sublingually with CBD oil tinctures.
CBDistillery has not provided any information regarding certifications this brand may have received for its manufacturing facilities.
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