Instead, CBD has been credited with relieving numerous medical conditions, such as epilepsy, anxiety, inflammation, insomnia, and pain. Although “credited” does not mean proven. Because of the historical regulatory landscape, there are hardly any well-conducted trials backing up those claims, although research is expected to ramp up now that laws distinguish between hemp and marijuana.
Conclusion: CBD may help with depression but more trials are needed.
What is CBD?
Unfortunately, few human trials investigating the use of CBD as a single agent to relieve pain exist, with most trials using a combination of CBD and THC to relieve pain. Notably, Health Canada has approved a combination medication that contains both THC and CBD in a 1:1 ratio for the relief of central nerve-related pain in multiple sclerosis, and cancer pain that is unresponsive to optimized opioid therapy.
More recent research points to THC being more effective at reducing nausea and vomiting than CBD.
We look at nine medical conditions where CBD may be, or, has already proven to be, beneficial.
Summary: Effective – Academic research proves that CBD can help calm epilepsy.
Summary: Effective – Academic research proves that CBD might have neuroprotective properties.
Summary: No proof – there lacks enough academic research to prove this.
19. Reduce Symptoms of PTSD
Hence, cannabinoids protect the brain cells damage and keep the brain healthy and functioning correctly. CBD also has an anti-inflammatory effect on the brain.
Summary: Effective – Academic research proves that CBD can help treat lupus.
Several studies have shown that people who use cannabis regularly have a smaller waist circumference, a lower body mass index, and a reduced risk of obesity. In a report published in the American Journal of Epidemiology in 2011, a survey was done in more than 52000 participants that showed that the participants who use cannabis had about 1/3 lower rates of obesity  .
CBD has neuroprotective properties that help reduce damage to the brain  as well as the nervous system and helps encourage the growth and development of new neurons. Traumatic blows, ischemia, or genetic and autoimmune disorder can result in permanent or temporary neural damage.
Among the few human trials evaluating CBD’s anxiolytic effects was one published in the Brazilian Journal of Psychiatry in 2019. For this study, 57 men were given either CBD oil or a placebo before a public-speaking event. Anxiety was evaluated using physiological measures (such as blood pressure, heart rate, etc.) and a relatively reliable test for mood states known as the Visual Analog Mood Scale (VAMS).
Part of this response could be explained by the way that CBD acts in the brain. In low doses, CBD may act as an agonist to several receptor sites, meaning it acts similarly to surrounding molecules that normally bind to the receptor, enhancing the signalling of those receptor sites. At higher doses, however, too much activity at the receptor site can lead to an opposite effect, negating the beneficial effects of CBD.
Meredith Bull, ND, is a licensed naturopathic doctor with a private practice in Los Angeles, California.
According to a 2017 study in the Journal of the American Medical Association, only 30.95% of CBD products sold online were correctly labeled. Most contained less CBD than advertised, while 21.43% had significant amounts of THC.
Clinical research has shown that CBD oil can trigger side effects. Severity and type can vary from one person to the next.