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A study undertaken at the Complutense University in Madrid showed the effects of CBD in mice with ALS. The mice were administered small doses of CBD and the effects were monitored for a short period of time. They found that due to the CBD the progression of the disease in fact slowed down, extending the life expectancy of the mice by 6 days on average. This time frame was translated into three years for humans.
Amyotrophic Lateral Sclerosis, more commonly known as ALS or motor neurone disease, is a neurodegenerative disease that causes the depletion of the motor neurons in the body, i.e the neurons that are responsible for muscle movement. Although the average life expectancy is around 2-5 years after the initial diagnosis, (this is not the case for everyone look at Steven Hawkins for example!), several studies have shown that CBD can help to relieve some symptoms of ALS.
Symptoms of ALS
Despite this breakthrough there are still millions of people around the world that are suffering from this disease. The main symptoms of ALS include:
Many people around the world were unaware of what ALS was until 2015. A Facebook campaign called the ‘ice bucket challenge’ was recently launched to raise awareness of the disease. People all over the world including celebrities were having buckets of ice cold water thrown over them, to symbolise the feeling of the dying nerve endings that ALS sufferers have to endure on a daily basis. The campaign quickly became viral and has been one of the most successful in Facebook history, raising more than 100 million dollars and leading to the discovery of some ground breaking research.
CBD or cannabidiol has been known to ease severe pains and can bring some relief to the symptoms of ALS:
Información creada y revisada por expertos en Cannabis Medicinal. Todas las publicaciones se basan en investigaciones médicas y con referencias clínicas.
Rapidly emerging evidence is suggesting cannabinoids such as CBD and THC may reduce neurological and oxidative damage associated with ALS.
Stephen Hawking had the condition for most of his life but ultimately passed away at the age of 76.
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Therefore, we recommend opting for a full-spectrum CBD oil rather than a purified CBD extract with all other cannabinoids and terpenes removed. But depending on where you live, you may or may not have access to CBD products that contain THC in concentrations higher than about 0.3%.
We recommend starting with a low dose and building up gradually by adding 2 mg to 5 mg of CBD each day. Once symptoms are alleviated, you’ve found the right dose. According to case reports, CBD can relieve symptoms such as insomnia, pain, and muscle tremors almost immediately, while the longevity-enhancing effects of the compound would take much longer and won’t be as noticeable. Further research would be needed to confirm these kinds of effects.
The disease involves gradual muscle paralysis as the neurons controlling the muscles break down. We each have millions of specialized nerve cells — called motor neurons — tasked with transmitting messages from the brain to the muscles and back again.
The researchers found that delta-9-tetrahydrocannabinol (THC), cannabinol (CBN), Sativex (a 1:1 mixture of THC and CBD), and other compounds had positive effects. They included reducing oxidative stress, protecting the nervous system, and slowing disease progression.
Another potential benefit of CBD for ALS patients is its ability to regulate the immune system and quell inflammation. Experts have suggested that immune dysfunction may contribute to the development of ALS and research has shown that people with the condition often have excessive levels of inflammation.
For starters, THC’s psychogenic effects can potentially be a problem for those with ALS. While some people may find the high pleasant, others may not enjoy the sensation. Furthermore, THC can cause various side effects, including dizziness, confusion, or increased anxiety levels.
What Do the Studies Say?
CBD is a chemical compound that works with the body to produce a variety of beneficial effects, many of which can mitigate symptoms.
Finally, a 2019 study investigated the effects of CBD with THC on spasticity in 32 ALS patients. It found that there was a high level of satisfaction with the treatment, especially among those with moderate to severe symptoms. The researchers state that “THC:CBD may serve as a valuable addition in the spectrum of symptomatic therapy in ALS.” However, they also suggest that further research is necessary.
While there are many people who smoke cannabis regularly to manage many of the underlying symptoms of ALS, there are a few significant drawbacks that make taking CBD oil a preferable option.
However, CBD may address the side effects of drugs such as Riluzole, allowing patients to have less stress and discomfort. CBD may assist in making patients’ lives easier, allowing doctors and specialists to concentrate on long-range options and care.