The Federal Drug Administration does not regulate CBD, so you should always be diligent when selecting a source. Always buy your product from a reputable company that offers organic CBD. Look for companies that offer third-party testing to make sure that the product is accurately labeled and dosed. Start with 5–10 mg per day for anxiety reduction and increase your dose by 5 mg a day to find your sweet spot.
CBD oil is a strong inhibitor of P450 enzymes, which are the main enzymes that break down benzodiazepines and other drugs. When you take CBD oil, it binds to these enzymes, which can interfere with the way the drugs are metabolized in your body. Simply put, CBD oil can prevent your body from effectively breaking down drugs like benzodiazepines.
Xanax is taken orally and metabolized in the liver by an enzyme called P4503A4.
CBD Dosage for Anxiety
CBD works by influencing our endocannabinoid system, which helps us maintain a state of internal balance.
CBD has been shown to have stress-reducing effects in various populations and across a wide range of health conditions (17).
Due to the high risk of addiction and multiple side effects of Xanax, you may be interested in replacing your Xanax prescription with CBD. Xanax is a very potent anti-anxiety medication that comes with a lot of risks. CBD has less dramatic effects on anxiety reduction but comes with many health-promoting benefits.
You can safely use topical CBD with other drugs since topical CBD does not get in your bloodstream and will not inhibit P450 enzymes.
While doctors mainly prescribe it to humans, some vets also use Xanax when treating dogs that suffer from panic attacks. However, the FDA does not recognize Xanax as veterinary medicine, so it’s best to avoid giving it to animals.
Alprazolam, better known as Xanax, is a benzodiazepine — a medicine used to treat anxiety and depression. It’s also known as a central nervous system depressant because it acts on the brain and nerves and calms them down.
What Is Xanax?
Unfortunately, using CBD and Xanax together is not a good idea. When Xanax enters your body, a liver enzyme called CYP3A4 breaks it down. CBD also reacts with this enzyme — it inhibits its activity, thus ensuring that Xanax stays in the bloodstream longer.
As stated before, Xanax is quite effective at treating anxiety and depression. People with these conditions may have certain chemical imbalances in the brain, causing them to feel unwell. Xanax helps to correct those and lets them live a happier, more fulfilling life.
If you suffer from anxiety or depression, you’re probably always searching for new ways to make yourself feel better. There’s no doubt that you’ve heard of CBD — everyone’s claiming that it works miracles for mental health. But you’re already taking medication, and you’re not sure how well CBD and Xanax go together. If that’s the case, read on to find out!
While generally considered safe, CBD may cause drowsiness, lightheadedness, nausea, diarrhea, dry mouth, and, in rare instances, damage to the liver. Taking CBD with other medications that have similar side effects may increase the risk of unwanted symptoms or toxicity. In other words, taking CBD at the same time with OTC or prescription medications and substances that cause sleepiness, such as opioids, benzodiazepines (such as Xanax or Ativan), antipsychotics, antidepressants, antihistamines (such as Benadryl), or alcohol may lead to increased sleepiness, fatigue, and possibly accidental falls and accidents when driving. Increased sedation and tiredness may also happen when using certain herbal supplements, such as kava, melatonin, and St. John’s wort. Taking CBD with stimulants (such as Adderall) may lead to decreased appetite, while taking it with the diabetes drug metformin or certain heartburn drugs (such as Prilosec) may increase the risk of diarrhea.
Products containing cannabidiol (CBD) seem to be all the rage these days, promising relief from a wide range of maladies, from insomnia and hot flashes to chronic pain and seizures. Some of these claims have merit to them, while some of them are just hype. But it won’t hurt to try, right? Well, not so fast. CBD is a biologically active compound, and as such, it may also have unintended consequences. These include known side effects of CBD, but also unintended interactions with supplements, herbal products, and over-the-counter (OTC) and prescription medications.
Doubling up on side effects
The researchers further warned that while the list may be used as a starting point to identify potential drug interactions with marijuana or CBD oil, plant-derived cannabinoid products may deliver highly variable cannabinoid concentrations (unlike the FDA-regulated prescription cannabinoid medications previously mentioned), and may contain many other compounds that can increase the risk of unintended drug interactions.
Many drugs are broken down by enzymes in the liver, and CBD may compete for or interfere with these enzymes, leading to too much or not enough of the drug in the body, called altered concentration. The altered concentration, in turn, may lead to the medication not working, or an increased risk of side effects. Such drug interactions are usually hard to predict but can cause unpleasant and sometimes serious problems.
Researchers from Penn State College of Medicine evaluated existing information on five prescription CBD and delta-9-tetrahydrocannabinol (THC) cannabinoid medications: antinausea medications used during cancer treatment (Marinol, Syndros, Cesamet); a medication used primarily for muscle spasms in multiple sclerosis (Sativex, which is not currently available in the US, but available in other countries); and an antiseizure medication (Epidiolex). Overall, the researchers identified 139 medications that may be affected by cannabinoids. This list was further narrowed to 57 medications, for which altered concentration can be dangerous. The list contains a variety of drugs from heart medications to antibiotics, although not all the drugs on the list may be affected by CBD-only products (some are only affected by THC). Potentially serious drug interactions with CBD included