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There have been reports that cannabinoids like THC and CBD may be helpful for nausea and vomiting and anorexia, as well as neuropathy, anxiety, depression and insomnia. Synthetic cannabinoids like dronabinol have been approved for use with chemotherapy-induced nausea and vomiting, but have not been shown to be superior to conventional anti-nausea medications.
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Second, if a lab produces both CBD and THC products, there can be cross-contamination — whether it’s through extraction, handling or packaging.
Yes. Epidiolex. It was originally approved in 2018 for the treatment of two conditions, both related to epilepsy: Lennox-Gastaut syndrome and Dravet syndrome. But aside from Epidiolex, no CBD product has been approved by the FDA for any other medical purpose.
Quality, cleanliness and regulation are the biggest concerns.
All of his patients who are taking cannabis palliatively have reported that it is effective, Blondin said. Among those using cannabis therapeutically, he said, all seven glioblastoma patients were alive at data cutoff; their cannabis use had ranged from two to 30 months.
Working Through Challenges
“I mention the option to patients to use with standard treatment when diagnosed, and see if they’re interested, or if their families want them to try it,” he said. He advises against cannabis if the patient has a history of addiction or psychiatric or cognitive disabilities, but considers most he treats to be eligible.
When patients are interested, Blondin registers them with the state, which allows them to buy cannabis at Connecticut dispensaries.