The earliest studies proving the effectiveness of cannabis compounds in the treatment of convulsions came from animal research from the 1970s. The researchers analyzed the anticonvulsant properties of both THC and CBD oils, concluding that both extracts had substantial effects on mice.
The good news, though, is that for two-thirds of participants, the CBD proved effective in the long run.
To my surprise, 1 mL a day split into two doses was enough to boost my resistance to stress and the outside stimuli. After two weeks, I slightly decreased the dosage and was still getting pretty good results. This was the first time a potency lower 1500 mg lasted more than 1 month for me.
What the Research Says
Low-Dose Initiation instructions:
CBDistillery has many different forms of CBD, from sublingual tinctures to capsules, gummies, topicals, and vapes. Their CBD oil is available as ‘full-spectrum’ or isolate.
With such a wide potency range, CBDistillery oils may suit both novice and experienced consumers alike. The only downside to the company’s product range is that they’re not made with organic hemp.
If you want to use CBD in a more natural form to see how it works for your symptoms, you may try the following formats:
CBD desensitizes TRPV1 channels. The TRPV1 channels determine how your body experiences pain and are located throughout your central nervous system and brain. People who have epilepsy have more TRPV1 receptors in the temporal lobes of their brains than those who do not have epilepsy.
They third-party test all of their products to guarantee freshness and purity to their customers and even provide a downloadable version of their test to any given location.
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CBD Oil for Non-Epileptic Seizures
Cannabis oil may have unwanted levels of THC in it, which, in some studies, has precipitated seizures and caused increased anxiety. Hemp derived oil comes from the agricultural hemp plant, a plant different in composition than the cannabis plant since hemp is bred to contain minimal amounts of THC.
Because of the FDA ruling, it is not legal to propose dosages for CBD where we are not dealing with an FDA-approved medical condition attributed to a drug. The only drug to receive FDA approval for the treatment of epilepsy is Epidiolex, a plant-derived source of pure CBD.
The oils come in four flavors and three strengths. Natural, Strawberry, Cookies and Cream, and Mint top the flavor list. The strengths come in 250, 600 and 1000 mg. The supplements come in doses of 15mg-750 mg per 30-tablet bottle.
Hemp derived extract was given to 138 patients for epileptic seizures  . Sixty-eight percent of the study respondents reported decreased seizure severity or frequency from the effects of CBD. About 2/3 reported other effects of CBD such as better sleep and improved alertness. Adverse events were reported by 22% and included diarrhea, fatigue, and increased seizures.
In the next section, we’ll discuss the relationship between epilepsy and the endocannabinoid system, the body’s prime homeostatic network.
The Epidiolex studies targeted the treatment of two major types of epilepsy: Dravet syndrome and Lennox-Gastaut syndrome, both of which are prevalent in children.
Now, CBD can be extracted from marijuana and hemp, both of which belong to the Cannabis sativa L. family. Marijuana contains high levels of THC and its legal status is a bit hazy. On the federal level, marijuana is considered a Schedule 1 substance, meaning it’s illegal and punishable with prison and hefty fines. Individual states can regulate marijuana on their own. So far, 11 states have legalized the recreational use of marijuana, while 37 states have a medical marijuana program.
What solvents have been used for making your CBD oil?
A 2017 study in The Journal of Epilepsy Research showed improvements in seizure control among patients with specific epilepsy disorders. However, researchers indicated that their study was inconclusive because they weren’t able to decide if the reduction in seizures was a direct effect of CBD treatment.
Epidiolex was the first CBD-based drug tested in controlled clinical trials, meaning that it involved two groups of patients. The control group was treated with a placebo, while the other one took a dose of CBD for their seizures. On top of this, the trials were double-blind and randomized, so researchers didn’t have any information about who was in the CBD group and who was receiving the placebo.
As mentioned, in December 2018 the government removed hemp and hemp-derived CBD from Schedule I of the Controlled Substances Act. Before that removal, human trials regarding the use of CBD for epilepsy were limited.