You’re probably already familiar with tetrahydrocannabinol, or THC, which is another compound found in the cannabis plant and its main psychoactive component. But unlike THC, CBD is not psychoactive. In other words, it’s not what gets you stoned. It’s also different from medical marijuana, which has been shown to reduce pain.
The law depends on where you live, and whether the CBD comes from hemp or marijuana. The Farm Bill of 2018 legalized hemp. Marijuana is trickier because the federal government still considers it an illegal drug, although states have their own swiftly changing laws. Some states have legalized recreational use of marijuana, while others have legalized medical marijuana. Still others have introduced CBD-specific legislation.
What is CBD?
Celebrities are also getting in on the craze. Martha Stewart recently released a line of CBD wellness products. Rob Gronkowski has one, too.
CBD can be taken orally or applied topically, depending on the product. There are lots of options out there, from gummies and softgels that supposedly ease anxiety to calming bath soaks, creams and oils — and even beer.
In addition to treating epilepsy, research has shown CBD may help reduce anxiety for people who have schizophrenia or psychosis, or who are addicted to opiates.
Side effects of CBD include nausea, fatigue and irritability. CBD can increase the level in your blood of the blood thinner coumadin, and it can raise levels of certain other medications in your blood by the exact same mechanism that grapefruit juice does. A significant safety concern with CBD is that it is primarily marketed and sold as a supplement, not a medication. Currently, the FDA does not regulate the safety and purity of dietary supplements. So, you cannot know for sure that the product you buy has active ingredients at the dose listed on the label. In addition, the product may contain other (unknown) elements. We also don’t know the most effective therapeutic dose of CBD for any particular medical condition.
CBD may offer an option for treating different types of chronic pain. A study from the European Journal of Pain showed, using an animal model, CBD applied on the skin could help lower pain and inflammation due to arthritis. Another study demonstrated the mechanism by which CBD inhibits inflammatory and neuropathic pain, two of the most difficult types of chronic pain to treat. More study in humans is needed in this area to substantiate the claims of CBD proponents about pain control.
CBD has been touted for a wide variety of health issues, but the strongest scientific evidence is for its effectiveness in treating some of the cruelest childhood epilepsy syndromes, such as Dravet syndrome and Lennox-Gastaut syndrome (LGS), which typically don’t respond to antiseizure medications. In numerous studies, CBD was able to reduce the number of seizures, and, in some cases, it was able to stop them altogether. Videos of the effects of CBD on these children and their seizures are readily available on the Internet for viewing, and they are quite striking. Recently the FDA approved the first ever cannabis-derived medicine for these conditions, Epidiolex, which contains CBD.
Is CBD safe?
CBD stands for cannabidiol. It is the second most prevalent of the active ingredients of cannabis (marijuana). While CBD is an essential component of medical marijuana, it is derived directly from the hemp plant, which is a cousin of the marijuana plant. While CBD is a component of marijuana (one of hundreds), by itself it does not cause a "high." According to a report from the World Health Organization, "In humans, CBD exhibits no effects indicative of any abuse or dependence potential…. To date, there is no evidence of public health related problems associated with the use of pure CBD."
Some CBD manufacturers have come under government scrutiny for wild, indefensible claims, such that CBD is a cure-all for cancer, which it is not. We need more research but CBD may be prove to be an option for managing anxiety, insomnia, and chronic pain. Without sufficient high-quality evidence in human studies we can’t pinpoint effective doses, and because CBD is currently is mostly available as an unregulated supplement, it’s difficult to know exactly what you are getting. If you decide to try CBD, talk with your doctor — if for no other reason than to make sure it won’t affect other medications you are taking.
CBD is commonly used to address anxiety, and for patients who suffer through the misery of insomnia, studies suggest that CBD may help with both falling asleep and staying asleep.
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“CBD is CBD. The human body does not care where the molecule comes from”
CBD is one of 113 other cannabinoids. Cannabinoids are chemicals which act upon certain receptors in the human body and brain, known as cannabinoid receptors.
Using ethanol is cheaper than CO2 extraction, but there are some disadvantages. For one, the process may reduce the potency of the oil, as it can damage certain waxes in the plant. Secondly, unwanted chlorophyll is co-extracted from the cannabis, which results in the oil having an unpleasant flavour. Removing the chlorophyll poses an additional cost and reduces the potency of the CBD oil further.
Disadvantages of CBD oil from hemp:
CBD isolate (crystal, slab or shatter) is the most pure form of CBD you can buy. CBD isolate benefits include being THC free, cheaper & able to be used to make DIY CBD products.
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Isolated CBD is not necessarily a better product than a full-spectrum CBD oil, which also contains an array of different compounds from the cannabis plant. The organic chemist Raphael Mechoulam – who is responsible for discovering how THC interacts with the human body – suspects that the medicinal benefit from CBD is enhanced when it is consumed in conjunction with THC and other cannabinoids and terpenoids found in marijuana. Mechoulam has referred to the phenomenon of cannabinoids working in a positive way together as the ‘entourage effect’.
Some suppliers produce hemp oils that contain 0% THC, potentially a safe choice for minors or those who undergo regular drug testing.
The main advantage of taking CBD isolate is being able to use it as a base ingredient to make your own CBD products, for example, you can add it to your favourite vape e-juice. Additionally, there are many different ways to dose using it: how to use CBD isolate .