CBD oil contains CBD mixed with an inert carrier oil, such as coconut oil or hemp seed oil. The bottled oil, called a tincture, is sold in various concentrations. There are also CBD capsules, CBD gummies, and under-the-tongue CBD sprays.
Cathy Wong is a nutritionist and wellness expert. Her work is regularly featured in media such as First For Women, Woman's World, and Natural Health.
CBD oil may benefit those with drug addiction, suggests a 2015 review of studies published in Substance Abuse.
There is some evidence that CBD interacts with seizure medications such as Onfi (clobazam) and boosts their concentration in the blood. Further research is needed.
According to a 2017 study in the Journal of the American Medical Association, only 30.95% of CBD products sold online were correctly labeled. Most contained less CBD than advertised, while 21.43% had significant amounts of THC.
Because CBD supplements come in so many different forms—such as oils, gummies, tinctures, and vapors—the amount that’s actually absorbed can vary drastically. This, combined with each person, will ultimately affect which (if any) CBD side effects you might experience.
“Since discovering the endocannabinoid system (ECS) in the body in the 1990s, CBD has been researched more extensively. The ECS is a central regulatory system restoring normal balance and homeostasis in a range of human physiologic systems throughout the body and brain and has cannabinoid receptors and chemicals in its function,” explains Dr. Matharu-Daley.
Can Interact With Other Medications
In some cases, those who ingest CBD supplements might experience nausea, says Dr. Matharu-Daley. This depends on how sensitive the person is to CBD, as well as the amount they ingest.
CBD is technically an unregulated substance in the United States and therefore it ought to be used with caution. This is especially important for those taking additional medications and/or those with ongoing medical issues. That said, preliminary research on CBD and its benefits are promising in relation to helping with mild to moderate health concerns and it is generally considered a safe substance. Health professionals do not consider CBD a cure-all for serious medical issues, including cancer.
The most comment side effects of CBD include drowsiness, gastrointestinal issues, dry mouth, reduced appetite, nausea, and interaction with other medications. Those are outlined in detail below.
You take prescription drugs. (Could be important) Pharmaceutical drugs are processed by your body in different ways; some are less effective after processing, while others aren’t effective until after they’ve been processed. Similar to grapefruits, CBD can occupy enzymes (cytochrome p450) that your body uses to process certain pharmaceutical drugs. Taking CBD alongside these pharmaceuticals could pose a health risk by either increasing or decreasing levels of these medications in your bloodstream. If you currently take prescription drugs — particularly *any that come with a warning not to consume with grapefruit* such as warfarin, anti-epileptics, HIV antivirals, chemotherapy and others — we suggest speaking with a medical professional before incorporating CBD into your wellness routine. They could help you understand potential interactions and how to proceed.
Because we lack clinical evidence in favor of CBD, we also lack clinical evidence against CBD. From the few clinical trials that have been conducted, no conclusive severe side effects have surfaced.
True CBD products are prepared from hemp plants, which can contain trace quantities of THC unless that’s removed during extraction. If a product contains high levels of THC, you might experience side effects like dry mouth, hunger, or altered mood and thinking.
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The most comprehensive results available are based on Epidiolex, the FDA-approved CBD drug for childhood epilepsy. During clinical trials, youths between ages 2 and 18 were prescribed high daily doses of CBD for 14 weeks. The daily doses were equivalent to 1,360 mg for a 150-pound adult — more than is typically found in an entire bottle of CBD oil.
Side effects based on high-dose clinical trials
For most patients, these side effects occurred during the first few weeks while they were quickly raising their dosage. The symptoms typically subsided after their dosage stabilized, and lowering the dose was also an effective way of decreasing undesirable side effects. If you’re experiencing any of these side effects on your current CBD product, you might experiment with waiting it out a week, lowering your dose or trying a different type of product entirely.
So yes, you may be jumping the gun by taking CBD to address a health issue when its use is not yet supported by clinical evidence that would pass muster with the FDA. But that clinical evidence won’t be available any time soon, and many people don’t want to wait a decade before finding out for themselves if CBD is effective for their needs.