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epidiolex alternative

The present disclosure relates to the use of cannabidiol (CBD) for the reduction of total convulsive seizure frequency in the treatment of “treatment-resistant epilepsy” (TRE). In particular, the disclosure relates to the use of CBD of treating TRE when the TRE is Dravet syndrome; myoclonic absence seizures or febrile infection related epilepsy syndrome (FIRES). The disclosure further relates to the use of CBD in combination with one or more anti-epileptic drugs (AEDs).

Patent expiration dates:

The present disclosure relates to the use of cannabidiol (CBD) for the treatment of atonic seizures. In particular the CBD appears particularly effective in reducing atonic seizures in patients suffering with etiologies that include: Lennox-Gastaut Syndrome; Tuberous Sclerosis Complex; Dravet Syndrome; Doose Syndrome; Aicardi syndrome; CDKL5 and Dup15q in comparison to other seizure types. The disclosure further relates to the use of CBD in combination with one or more anti-epileptic drugs (AEDs).

Glossary

Exclusivity is exclusive marketing rights granted by the FDA upon approval of a drug and can run concurrently with a patent or not. Exclusivity is a statutory provision and is granted to an NDA applicant if statutory requirements are met.

Patent expiration dates:

Patent expiration dates:

Patents are granted by the U.S. Patent and Trademark Office at any time during a drug’s development and may include a wide range of claims.

Do not use Epidiolex for other reasons or if not prescribed by a licensed health care provider.

People who take Epidiolex may test positive for cannabis drug screens. Tell the person giving the drug test that you are taking Epidiolex for a medical reason.

Using alcohol and other products that depress the central nervous system or brain activity (CNS depressants) while taking Epidiolex can increase sleepiness or sedation.

How To Take:

The dose in children is based on weight, written as milligrams per kilograms or “mg per kg”. It is important to follow the instructions given by the prescribing health care provider.

EPIDIOLEX is a prescription medicine that is used to treat seizures associated with Lennox-Gastaut syndrome, Dravet syndrome, or tuberous sclerosis complex in patients 1 year of age and older.

Epidiolex ® (EH-peh_DYE-oh-lex) oral solution CV is the brand name for the cannabidiol oral solution, also referred to as CBD, from Greenwich Biosciences. The name or look may be different in other countries, but the dose (measured in milligrams, abbreviation “mg”) usually will be the same. Epidiolex is a quality grade of cannabidiol oil that is different from CBD or cannabidiol that is not U.S. Food and Drug Administration (FDA) approved.

Seizures during pregnancy: Some women may have more seizures during pregnancy, because of hormone changes and how seizure medicine is handled by your body. Blood levels of seizure medicine may need to be checked more regularly during pregnancy so the dose can be adjusted if needed.