However, the effect of CBD on each addiction type was often very different. With opioid addiction, for example, CBD showed little effect in minimizing withdrawal symptoms in the absence of THC. By contrast, CBD on its own appeared effective in minimizing drug-seeking behaviors in users of cocaine, methamphetamine, and other psychostimulant drugs.
In June 2018, the U.S. Food and Drug Administration (FDA) approved Epidiolex, a CBD oral solution used for the treatment of certain rare forms of epilepsy in children under 2—Dravet syndrome and Lennox-Gastaut syndrome. Both are exceptionally rare genetic disorders causing lifelong catastrophic seizures that begin during the first year of life.
Many of these interactions are mild and require no adjustment to treatment. Others may require a drug substitution or the separation of doses by several hours.
CBD oil should be avoided during pregnancy and breastfeeding. A 2018 study from the American Academy of Pediatrics warned women to avoid marijuana during pregnancy due to the potential risks to a baby’s development. Although it is unclear how CBD contributes, CBD is known to pass through the placental barrier.
Scientists believe that CBD reduces nerve pain by binding to glycine receptors in the brain that regulate the speed at which nerve signals pass between nerve cells.
Advances in Pharmacological Sciences: “Review of Anti-Inflammatory Herbal Medicines.”
Omega-3 fatty acids abundant in hemp seed oil can help lower blood pressure in people with hypertension (high blood pressure). Research recommends using omega-3 fatty acid supplements along with blood pressure medicine to lower blood pressure.
Reviews in Obstetrics and Gynecology: “Omega-3 Fatty Acids and Pregnancy.”
Amounts and Dosage
Experts agree that this 3:1 fatty acid ratio is ideal for health benefits in humans.
As with any oral supplement, be sure to talk to your healthcare provider before consuming hemp seed oil.
The amount of hemp seed oil you take depends on how you use it and what health benefits you would like to obtain. Researchers estimate that three tablespoons of hemp seed oil per day can provide the amount of 3:1 fatty acid ratio needed for a healthy diet.
Hemp seed oil is rich in linoleic acid. Studies have shown that eating a diet high in linoleic acid significantly reduces total cholesterol and low-density lipoprotein (LDL), or “bad” cholesterol.
Some people experience skin irritation when using topical oils containing CBD, possibly due to an allergy. Start with using a small amount to see how your skin reacts to it, and keep an eye on any changes.
Brain, Behavior, and Immunity: “Omega-3 Supplementation Lowers Inflammation and Anxiety in Medical Students: A Randomized Controlled Trial.”
Improved Cardiovascular Health
Spreading hemp oil on your skin as a topical application can also reduce symptoms and provide relief for several types of skin disorders. One study showed that hemp oil can act as an effective acne treatment, though more research is needed in this area. In addition, consuming hemp seed oil was found to improve symptoms of atopic dermatitis, or eczema, due to the presence of the “good” polyunsaturated fats in the oil.
Current Pharmaceutical Biotechnology: “Gamma linolenic acid: an antiinflammatory omega-6 fatty acid.”
Mayo Clinic Proceedings: “Clinicians’ Guide to Cannabidiol and Hemp Oils.”