After reducing the size of CBD molecules, those CBD nanoparticles are then placed into a fatty emulsifier—where it dissolves in fat—so that, upon consumption, it reaches the bloodstream very quickly. This is what makes it possible for CBD and the water in the bloodstream to mix.
Rubbing CBD balms and creams into your skin—applying oil-based products topically allows the absorption of CBD through the skin, thus delivering the substance directly into your system. This method doesn’t inhibit first-pass concentration reduction at all.
One of the ruling ways to overcome the first-pass effect is to convert the naturally oil-soluble CBD extract into a water-soluble form. This makes sense because the average adult is anywhere from 50–65% water. So, w ater-soluble CBD is absorbed into your stomach and lymphatic system easier and at a higher concentration than the oil-based products.
What to Look for (and what to avoid) in Water-Soluble Products
We lose the bioavailability of vitamins and supplements (CBD included) through something called the first-pass metabolism effect . The first-pass metabolism effect is when supplements are metabolized at a specific location in the body that results in a reduced concentration of the product once it does reach its site of action or the systemic circulation.
Not only are more of these nano-sized CBD particles reaching the bloodstream at a higher rate, but they’re getting there faster because they don’t need to latch onto fat and slowly digest over time. These nano-sized CBD particles are absorbed at a higher rate and rapidly , at a 5x-10x absorption rate potency. This superior absorption and fast action make it easier to take your daily CBD dosage with water, coffee, or any other beverage that can be sipped on while bustling through the day.
Dropping some tincture under the tongue and allowing it to absorb through your salivary glands is less affected by the first-pass metabolism as well. We know supplement regimes are sacred to each individual and it’s hard to make a change from something you already love, but there are ways to ensure you’re getting optimal use out of your supplement favorites (woohoo!).
Additional ingredients and processing are necessary to achieve this nanoparticle sizing, so it’s important to know what to look for when considering Water-Soluble CBD. Organic hemp-derived CBD is vastly different from conventional CBD that is available nearly everywhere nowadays (including gas stations- stay away!). To ensure that your product experience is optimally safe, always look for clean, natural ingredients, and 3rd party testing certification.
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