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phytocannabinoids side effects

CBD oil may be used both ways.

The takeaway about CBD is that the initial research is promising but there is still much to learn. It may help with some conditions like long-term pain and sleep.

Types of CBD

Applications of transdermal cannabidiol were studied in people with temporomandibular (joint of the jaw) disorders (TMD) that caused myofascial (coverings of muscle) pain. Those studied had less muscle activity and pain after applying the topical CBD for 2 weeks.

An animal study found transdermal CBD lessened the pain and inflammation of arthritis.

CAUTION: CBD should not be taken by people with liver disease or Parkinson's disease.

Studies have also shown that phytocannabinoids may interact with 5-HT receptors similarly to how antidepressants and selective serotonin reuptake inhibitors (SSRIs) do. This means that phytocannabinoids and SSRIs may significantly inhibit serotonin’s reuptake and maintain its levels in the body. Scientists attribute anxiety and depression to low serotonin levels, and phytocannabinoids may go a long way in managing these conditions.

Recently, researchers studied the structure of phytocannabinoids like CBD in an attempt to understand how they work. CBD’s structure was found to be incredibly similar to the structure of nonsteroidal anti-inflammatory drugs (NSAIDs) used to alleviate inflammation. It was therefore concluded that phytocannabinoids like CBD may help with pain and inflammation management. Phytocannabinoid oil may, therefore, be great for managing conditions like arthritis and neuropathic pain.

Phytocannabinoid oil is generally safe and legal since it is non-psychoactive. However, some common side effects among users could include nausea, fatigue, and drowsiness. However, these are usually mild and a result of taking higher doses.

Improved Sleep Quality

Tetrahydrocannabinol is a psychoactive cannabinoid responsible for the “high” associated with marijuana. However, THC levels in phytocannabinoid oil are low (0.3% or less), just like other industrial hemp products.

Phytocannabinoids, including CBD and THC, may be attributed to the activation of neuronal CB1 receptors. In turn, this activation has the potential to reduce neurotransmitter release through the blockage of various channels. Ultimately, the activation of CB1 receptors may inhibit neurotransmission and suppress neuronal excitability. With effects, phytocannabinoids have been thought to have the potential to modulate various neurodegenerative conditions like Huntington’s and Parkinson’s disease. Some phytocannabinoids may also have potential anti-epileptic and anticonvulsant properties and might help manage epilepsy and seizures.

Cannabidiolic acid is the acidic precursor of CBD found in raw and unprocessed hemp plants. CBDA is converted to CBD through decarboxylation, as it breaks down when exposed to high temperatures. It is also non-psychoactive and has loads of potential benefits.

The interaction of phytocannabinoids with 5-HT receptors is suggested to have a positive effect on gastrointestinal distress. Particularly, cannabinoids may be used to help relieve nausea and emesis from gastrointestinal distress caused by other medications or chemotherapy. Therefore, phytocannabinoids have the potential to help cancer patients continue with treatment without getting overwhelmed by chemotherapy-induced nausea and vomiting.