Also called cannabis sativa oil, it contains zero percent THC and is completely void of CBD (or contains only trace amounts).
Broad-Spectrum CBD: Robust calming effect at a higher price point, derived from the “whole plant”
Hemp Seed Oil
CBD Isolate: Treats acne and inflammation, separation from all other components of the cannabis plant makes it more pure
CBD (cannabidiol) in its purest form, isolated from other elements found in the plant it was derived from.
However, support for the entourage effect has been mixed. Scientists disagree when it comes to determining whether or not the other cannabinoids matter. Continuing the musical metaphor, it could be an orchestra of people who don’t know how to play—there just isn’t enough evidence for a sweeping declaration. Regardless, broad and full-spectrum CBD formulae are usually the ones most often used in products like tinctures, CBD vapes, and soothing creams—anywhere users want the “whole-plant” effect.
“Pure” CBD, also called “CBD isolate,” is called that because all other cannabinoids have been removed. So have terpenes and flavonoids, which give marijuana its strong aroma and earthy flavor.
Full spectrum CBD products for sale, including tinctures, topical creams, edible gummies and pet products. Smith Collection/Gado/Getty Images
Brandon McFadden receives funding from U.S. Department of Agriculture.
Hemp, marijuana and cannabanoidals
The current federal prohibition of marijuana, in other words, does not align with the public’s view – though state-based legalization shows that society is moving on without the blessing of politicians on Capitol Hill. U.S. recreational marijuana retail sales may reach US$8.7 billion in 2021, up from $6.7 billion in 2016.
Our recent study found that Americans perceive hemp and CBD to be more like over-the-counter medication and THC to be more like a prescription drug. Still, the average person in the U.S. does not view hemp, CBD, THC or even marijuana in the same light as illicit substances like meth and cocaine – even though both are classified by the DEA as having a lower potential for abuse than marijuana.
CBD comes in food, tinctures and oils, just to name a few. Here are some commonly used terms used to describe CBD products in the store.
The Drug Enforcement Agency categorizes cannabis as a Schedule 1 substance, meaning it handles cannabis as if there is no accepted medical use and a high potential for abuse. Scientists don’t know exactly how CBD works, nor how it interacts with other cannabinoids like THC to give marijuana its added therapeutic effects.
While there is hope for treating other conditions with the plant extract, Epidiolex remains the only CBD-derived drug approved by the F.D.A. Most of the research on cannabidiol has been in animals, and its current popularity has outpaced science. “We don’t have the 101 course on CBD quite figured out yet,” said Ryan Vandrey, an associate professor of psychiatry and behavioral sciences at Johns Hopkins University School of Medicine.
This year, 1,090 people have contacted poison control centers about CBD, according to the American Association of Poison Control Centers. Over a third are estimated to have received medical attention, and 46 were admitted into a critical care unit, possibly because of exposure to other products, or drug interactions. In addition, concern over 318 animals poured into the American Society for the Prevention of Cruelty to Animals’ Animal Poison Control Center.
However, a double-blind study found healthy volunteers administered CBD had little to no change in their emotional reaction to unpleasant images or words, compared to the placebo group. “If it’s a calming drug, it should change their responses to the stimuli,” said Harriet de Wit, co-author of the study and a professor in the University of Chicago’s department of psychiatry and behavioral neuroscience. “But it didn’t.”
Cannabidiol, or CBD, is the lesser-known child of the cannabis sativa plant; its more famous sibling, tetrahydrocannabinol, or THC, is the active ingredient in pot that catapults users’ “high.” With roots in Central Asia, the plant is believed to have been first used medicinally — or for rituals — around 750 B.C., though there are other estimates too.
Sleep can be disrupted for many reasons, including depression. Rodents seemed to adapt better to stressful conditions and exhibited less depressive-like behavior after taking CBD, according to a review in Journal of Chemical Neuroanatomy. “Surprisingly, CBD seems to act faster than conventional antidepressants,” wrote one of the authors of a new review, Sâmia Joca, a fellow at the Aarhus Institute of Advanced Studies in Denmark and an associate professor at the University of São Paulo in Brazil, in an email interview. Of course, it’s difficult to detect depression in animals, but the studies that Ms. Joca and her colleagues reviewed suggested that in models of chronic stress exposure, the mice and rats treated with CBD were more resilient.