Conclusion: CBD does not appear to interfere with sleep and may help people sleep better.
CBD derived from hemp contains no more than 0.3% THC and is legal federally but still illegal under some state laws. Cannabis-derived CBD products, on the other hand, are illegal federally but legal under some state laws.
Animal studies have shown that CBD has a positive effect on serotonin levels in the brain, and serotonin. Low levels of serotonin are thought to play a key role in mood as well as pain. 11
Medically reviewed by Carmen Fookes, BPharm. Last updated on Nov 2, 2020.
Conclusion: CBD may be beneficial at relieving pain but no high-quality human studies prove this.
More recent research points to THC being more effective at reducing nausea and vomiting than CBD.
Pretreatment with 300mg CBD significantly relieved anxiety in 57 healthy males who undertook a simulated public speaking test. However, dosages of 150mg CBD and 600mg CBD did not make any difference to the men’s anxiety levels. 7
If you and your veterinarian decide that you should try CBD as a treatment for your dog, there are a few things to keep in mind when purchasing CBD oil. Not all oils are the same; you’ll want high-quality CBD oil to have a better chance of it working.
The AKC’s Chief Veterinary Officer, Dr. Jerry Klein, explains what CBD oil is, what it does for dogs, and its safety concerns and potential side effects.
While there’s no scientific data on the side effects of CBD usage for dogs, there are potential side effects based on how CBD affects humans. To minimize any potential side effects, make sure you are following the proper dosage.
Risks of Using CBD Oil for Dogs
As with any pet wellness trend, when it comes to CBD oil for dogs, there’s a lot of information floating around the internet, and it’s difficult to know what’s accurate and what’s exaggeration. Of course, you want to do what’s best for your pup, which leads to the question: What do I need to know about CBD oil for dogs?
According to Dr. Klein, CBD is also used because of its anti-inflammatory properties, cardiac benefits, anti-nausea effects, appetite stimulation, anti-anxiety impact, and for possible anti-cancer benefits, although there’s no conclusive data on this use.
Learn more about the CBD study funded by the Canine Health Foundation.
The AKC Canine Health Foundation (CHF) is sponsoring a study through the Colorado State University’s College of Veterinary Medicine and Biomedical Sciences to evaluate the use of CBD in treatment-resistant epileptic dogs. The CHF hopes that this will be the first study to gain scientific data on the use of CBD in dogs with this condition.
Instead, CBD is thought to influence other receptors, including opioid receptors that regulate pain and glycine receptors involved in the regulation of the “feel-good” hormone and neurotransmitter serotonin.
There are no guidelines for the appropriate use of CBD oil. CBD oil is usually delivered sublingually (under the tongue). Most oils are sold in 30-milliliter (mL) bottles with a dropper cap.
The tricky part is calculating the exact amount of CBD per milliliter of oil. Some tinctures have concentrations of 1,500 mg per 30 mL, while others have 3,000 mg per mL (or more).
Scientists believe that CBD reduces nerve pain by binding to glycine receptors in the brain that regulate the speed at which nerve signals pass between nerve cells.
CBD oil may also increase liver enzymes (a marker of liver inflammation). People with liver disease should use CBD oil with caution, ideally under the care of a doctor who can regularly check blood liver enzyme levels.