Medical marijuana is frequently prescribed to people with intractable (treatment-resistant) pain, including those with terminal cancer. There is some evidence that CBD contributes to this benefit.
CBD oil may also increase liver enzymes (a marker of liver inflammation). People with liver disease should use CBD oil with caution, ideally under the care of a doctor who can regularly check blood liver enzyme levels.
Many of these interactions are mild and require no adjustment to treatment. Others may require a drug substitution or the separation of doses by several hours.
There is some evidence that CBD interacts with seizure medications such as Onfi (clobazam) and boosts their concentration in the blood. Further research is needed.
Part of this response could be explained by the way that CBD acts in the brain. In low doses, CBD may act as an agonist to several receptor sites, meaning it acts similarly to surrounding molecules that normally bind to the receptor, enhancing the signalling of those receptor sites. At higher doses, however, too much activity at the receptor site can lead to an opposite effect, negating the beneficial effects of CBD.
A tincture is a concentrated plant extract crafted by soaking the plant in a solvent such as alcohol or food-grade oils for several weeks. Photo by: Gina Coleman/Weedmaps
A tincture is also a smokeless, vapeless alternative that mitigates the potential harms associated with smoking and using a vape pen. There’s also virtually zero cleanup involved with a tincture, even when taken with morning coffee or an afternoon tea, making it an especially easy way to consume CBD.
When taking CBD tincture, keep the following pointers in mind to maximize its effects.
For example, a 30-milliliter bottle of CBD that contains 300 milligrams of CBD has 10 milligrams of CBD per one-milliliter dropper, the standard size for most bottle droppers. Knowing that, you can choose to use half a dropper (five milligrams) or whatever amount you desire and then adjust your dose with each use, as needed.
Ultimately, tinctures and CBD oil are similar in that they are both liquid forms of CBD extract, which can both be consumed in a variety of ways. The main differences have to do with how they are produced, and the type of liquid used to deliver the CBD to a consumer’s body.
Note: Alcohol fumes are combustible, so be sure to perform this recipe in a well-ventilated area.
We’re going to use this chart to help us figure out how much CBD tincture to take.
This biphasic idea may be new to some readers, but it isn’t all that uncommon. Alcohol, for example, is biphasic. Below a certain blood alcohol content (BAC), alcohol provides a stimulating effect. Above that blood alcohol content, it provides a depressant effect.
Can You Make Your Own CBD Tincture?
Once the alcohol and marijuana plant matter are combined, the alcohol dissolves the trichomes , cannabinoids, terpenes , flavonoids, and other chemical goodies and holds them in solution (kind of like mixing up a batch of Kool-Aid).
Side note: be sure to hold the liquid in your mouth, and don’t swallow. Nothing bad will happen if you do swallow; it will just take longer to feel the effects .
Technically, CBD does produce one other “side effect” of note: it can interfere with your liver’s ability to process other medications (a.k.a. hepatic metabolism). That could have unintended consequences if the CBD you’re taking isn’t meant to completely replace another medication (like heart or blood-pressure medication).
CBD tinctures don’t have any major side effects, so you don’t have to worry about feeling bad after just a few drops. And CBD tinctures are readily available at your local dispensary, so you don’t have to worry about where your supply will come from.